… We included 60 subcortical vascular cognitive impairment (… AD (remaining 121 subjects
with clinically normal cognition) … , the effects of Aβ positivity or tau burden on cognitive decline …

… to measuring cerebrovascular disease burden, such as the … of our analyses may be subject
to inherent challenges with … of limiting the impact of cerebrovascular disease on cognition. …

… Cognitive decline especially in the elderly individuals is … In patients with CAA, amyloid beta,
mainly composed of … dementia having AD and cerebrovascular disorder may be the most …

… of cerebrovascular disease (CVD) in terms of reduced stroke … cognitive impairment only
affected about a third of subjects, … Small-vessel lesions and amyloid burden independently …

… Aβ-positive (Aβ+) individuals could be grouped into the following … CSVD burden may have
an effect on cognitive impairment … Finally, we investigated the trajectories in cognition and MRI …

… capture only a portion of total cerebrovascular disease burden, since many … individuals with
both higher vascular risk and higher Aβ burden showed the steepest decline in cognition on …

… to individuals with subcortical vascular cognitive impairment. … although individuals with MCI
or AD had higher brain Aβ burden … MCI and AD with and without cerebrovascular disease. …

… individuals without dementia [32]. Therefore, it would be reasonable to expect that the effects
of … All participants in our SVCI cohort had severe CSVD burdens, which makes it difficult to …

… These potentially additive effects of Aβ and CeVD burden … unexplored in individuals with
normal cognition or MCI. … domain-specific cognitive impairment and NPS syndromes of positron …

… We analyzed plasma Aβ1 levels in 1201 subjects from two … associated with risk of stroke,
cognitive decline, dementia, and … , had higher burden of ischemic heart disease, and had more …